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PUBLIC HEALTH / RESEARCH LETTER
The mediating effect of depression on the association between lung disease and cardiovascular health
1
Department of Child Healthcare, Wenzhou People’s Hospital, Wenzhou, Zhejiang Province, China
2
Children’s Heart Center, The Second Hospital and Yuying Children’s Hospital, Institute of Cardiovascular Development and Translational Medicine, Wenzhou Medical University, Zhejiang, China
3
Department of Gastroenterology, Pingyang Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China
4
Department of Traditional Chinese Medicine, Wenzhou Yebo Proctology Hospital, Wenzhou, Zhejiang Province, China
These authors had equal contribution to this work
Submission date: 2024-04-15
Final revision date: 2024-06-09
Acceptance date: 2024-06-12
Online publication date: 2024-06-30
Arch Med Sci 2024;20(3):1029-1033
KEYWORDS
lung diseasescardiovascular healthdepressionNational Health and Nutrition Examination Surveymediating effect
TOPICS
ABSTRACT
Introduction:
In this study, we investigated the effect of depression on the interaction between lung disease and cardiovascular health (CVH).
Methods:
Utilising data from the National Health and Nutrition Examination Survey (2013–2018), we employed multivariate regression and bootstrap mediation analysis to explore the relationships among lung diseases, depression, and CVH scores.
Results:
Complex and significant associations were identified among lung diseases, depression, and CVH scores, with depression mediating 9.42% of the effect on CVH, especially for chronic bronchitis patients.
Conclusions:
Depression significantly mediated the relationship between lung disease and reduced CVH scores, highlighting the importance of mental health management in lung disease patients.
In this study, we investigated the effect of depression on the interaction between lung disease and cardiovascular health (CVH).
Methods:
Utilising data from the National Health and Nutrition Examination Survey (2013–2018), we employed multivariate regression and bootstrap mediation analysis to explore the relationships among lung diseases, depression, and CVH scores.
Results:
Complex and significant associations were identified among lung diseases, depression, and CVH scores, with depression mediating 9.42% of the effect on CVH, especially for chronic bronchitis patients.
Conclusions:
Depression significantly mediated the relationship between lung disease and reduced CVH scores, highlighting the importance of mental health management in lung disease patients.
REFERENCES (15)
1.
CDC. Asthma: most recent national asthma data. Centers for Disease Control and Prevention (CDC). Accessed 2024-02-13, https://www.cdc.gov/asthma/mos...
2.
Carter P, Lagan J, Fortune C, et al. Association of cardiovascular disease with respiratory disease. J Am Coll Cardiol 2019; 73: 2166-77.
3.
Zhang B, Li ZF, An ZY, et al. Association between asthma and all-cause mortality and cardiovascular disease morbidity and mortality: a meta-analysis of cohort studies. Front Cardiovasc Med 2022; 9: 861798.
4.
Fan W, Lee H, Lee A, Kieu C, Wong ND. Association of lung function and chronic obstructive pulmonary disease with American Heart Association’s Life’s Simple 7 cardiovascular health metrics. Respir Med 2017; 131: 85-93.
5.
Lloyd-Jones DM, Allen NB, Anderson CAM, et al. Life’s essential 8: updating and enhancing the American Heart Association’s Construct of cardiovascular health: a presidential advisory from the American Heart Association. Circulation 2022; 146: e18-43.
6.
Leung J, Gouda H, Chung JYC, Irmansyah I. Comorbidity between depressive symptoms and chronic conditions - findings from the Indonesia Family Life Survey. J Affect Disord 2021; 280: 236-40.
7.
Lotfaliany M, Bowe SJ, Kowal P, Orellana L, Berk M, Mohebbi M. Depression and chronic diseases: co-occurrence and communality of risk factors. J Affect Disorde 2018; 241: 461-8.
8.
O’Donnell DE, James MD, Milne KM, Neder JA. The pathophysiology of dyspnea and exercise intolerance in chronic obstructive pulmonary disease. Clin Chest Med 2019; 40: 343-66.
9.
Martinez-Garcia M, Faner R, Oscullo G, et al. Chronic bronchial infection and incident cardiovascular events in chronic obstructive pulmonary disease patients: a long-term observational study. Respirology 2021; 26: 776-85.
10.
Szucs B, Szucs C, Petrekanits M, Varga JT. Molecular characteristics and treatment of endothelial dysfunction in patients with COPD: a review article. Int J Mol Sci 2019; 20: 4329.
11.
Deng X, Fu J, Song Y, et al. Glucocorticoid receptor dysfunction orchestrates inflammasome effects on chronic obstructive pulmonary disease-induced depression: a potential mechanism underlying the cross talk between lung and brain. Brain Behav Immun 2019; 79: 195-206.
12.
Atlantis E, Shi Z, Penninx BJ, Wittert GA, Taylor A, Almeida OP. Chronic medical conditions mediate the association between depression and cardiovascular disease mortality. Soc Pychiatry Psychiatr Epidemiol 2012; 47: 615-25.
13.
Bucciarelli V, Caterino AL, Bianco F, et al. Depression and cardiovascular disease: the deep blue sea of women’s heart. Trends Cardiovasc Med 2020; 30: 170-6.
14.
Amadio P, Zarà M, Sandrini L, Ieraci A, Barbieri SS. Depression and Cardiovascular disease: the viewpoint of platelets. Int J Mol Sci 2020; 21: 7560.
15.
Carney RM, Freedland KE, Miller GE, Jaffe AS. Depression as a risk factor for cardiac mortality and morbidity: a review of potential mechanisms. J Psychosom Res 2002; 53: 897-902.
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| eISSN: | 1896-9151 |
| ISSN: | 1734-1922 |
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