Milk-alkali syndrome is characterized by the classic triad of hypercalcemia, metabolic alkalosis and impaired renal function, associated with ingestion of calcium and alkali. This syndrome was first recognized as a consequence of the treatment of peptic ulcer disease with milk and absorbable alkali. The replacement of the older peptic ulcer treatment with new agents became the syndrome rare in this group of patients but it is now increasingly prevalent in patients who use drugs containing calcium carbonate for prevention or treatment of osteoporosis. We describe a case of a middle age woman who admitted to our hospital with the classic features of milk alkali syndrome.