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SYSTEMATIC REVIEW/META-ANALYSIS
Impact of low-level laser therapy on upper limb lymphoedema secondary to breast cancer: a systematic review and meta-analysis
1
Department of Physical Therapy, College of Aplied Medical Sciences, University of Ha’il, Ha’il, Saudi Arabia
2
Department of Basic Sciences for Physical Therapy, Faculty of Physical Therapy, Cairo University, Giza, Egypt
3
Department of Diagnostic Radiology, College of Applied Medical Sciences, University of Ha’il, Hail, Saudi Arabia
4
Ahmed Foad Hospital, Egyptian Ministry of Health, Giza, Egypt
5
Department of Physical Therapy for Internal Medicine & Geriatrics, Faculty of Physical Therapy, Suez University, Suez, Egypt
6
Department of Physical Therapy, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia
7
Department of Physical Therapy, Cairo University Hospitals, Cairo University, Giza, Egypt
These authors had equal contribution to this work
Submission date: 2024-01-30
Final revision date: 2024-03-31
Acceptance date: 2024-04-06
Online publication date: 2024-05-13
Corresponding author
Ahmed Abdelmoniem Ibrahim
Department of Physical Therapy, College of Applied Medical Sciences, University of Ha’il, Ha’il, Saudi Arabia. Department of Physical Therapy, Cairo University Hospitals, Cairo University, Giza, Egypt., Egypt
Department of Physical Therapy, College of Applied Medical Sciences, University of Ha’il, Ha’il, Saudi Arabia. Department of Physical Therapy, Cairo University Hospitals, Cairo University, Giza, Egypt., Egypt
KEYWORDS
TOPICS
ABSTRACT
Introduction:
This review analysed the efficiency of low-level laser therapy in treating breast cancer-related lymphedema (BCRL) in women.
Material and methods:
Databases such as Scopus, PEDro, PubMed, Cochrane, and Web of Science were searched for RCTs using low-level laser therapy (LLLT) or photo-bio modulation therapy (PBMT) on BCRL published between 2010 and August 2023. Primary outcomes were arm circumference, volume, and hand grip strength, while secondary outcomes were pain, shoulder mobility, and quality of life.
Results:
Eleven RCTs with a total of 379 patients were analysed, and 8 studies were included for meta-analysis. We found no significant difference between laser-treated and control groups in any of the trials in terms of arm circumference, arm volume, grip strength, and quality of life post-intervention, and a significant difference between the groups in terms of pain intensity and shoulder mobility.
Conclusions:
This review revealed that low-level laser therapy (photobiostimulation) was successful in reducing arm circumference, volume, and pain, as well as enhancing grip strength, life quality, and mobility. However, the meta-analysis did not show any improvement except in pain and shoulder mobility. Further trials are required to assess the long- and short-term efficacy of LLLT in managing lymphoedema secondary to breast cancer.
This review analysed the efficiency of low-level laser therapy in treating breast cancer-related lymphedema (BCRL) in women.
Material and methods:
Databases such as Scopus, PEDro, PubMed, Cochrane, and Web of Science were searched for RCTs using low-level laser therapy (LLLT) or photo-bio modulation therapy (PBMT) on BCRL published between 2010 and August 2023. Primary outcomes were arm circumference, volume, and hand grip strength, while secondary outcomes were pain, shoulder mobility, and quality of life.
Results:
Eleven RCTs with a total of 379 patients were analysed, and 8 studies were included for meta-analysis. We found no significant difference between laser-treated and control groups in any of the trials in terms of arm circumference, arm volume, grip strength, and quality of life post-intervention, and a significant difference between the groups in terms of pain intensity and shoulder mobility.
Conclusions:
This review revealed that low-level laser therapy (photobiostimulation) was successful in reducing arm circumference, volume, and pain, as well as enhancing grip strength, life quality, and mobility. However, the meta-analysis did not show any improvement except in pain and shoulder mobility. Further trials are required to assess the long- and short-term efficacy of LLLT in managing lymphoedema secondary to breast cancer.
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