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LETTER TO THE EDITOR
Diagnostic value of methylated SEPT9 and RNF180 for gastric cancer in high-risk population: a multi-centre retrospective study in Yunnan, Southwest China
1
Mengzi People’s Hospital, Mengzi, China
2
Southern Central Hospital of Yunnan Province, Gejiu, China
3
The First People’s Hospital of Xundian Hui and Yi Autonomous County, Kunming, China
4
Chenggong District People’s Hospital, Kunming, China
5
Kaiyuan People’s Hospital, Kaiyuan, China
6
Gejiu People’s Hospital, Gejiu, China
7
First Affiliated Hospital of Kunming Medical Kunming, Kunming, China
8
The Affiliated Hospital of Yunnan University, Kunming, China
These authors had equal contribution to this work
Submission date: 2024-10-11
Final revision date: 2024-11-29
Acceptance date: 2024-12-03
Online publication date: 2024-12-31
Corresponding author
TOPICS
REFERENCES (12)
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Zhao L, Li M, Zhang S, Liu Y. Plasma-methylated SEPT9 for the noninvasive diagnosis of gastric cancer. J Clin Med 2022; 11: 6399.
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Shen SY, Singhania R, Fehringer G, et al. Sensitive tumour detection and classification using plasma cell-free DNA methylomes. Nature 2018; 563: 579-83.
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Wang X, Dong Y, Zhang H, et al. DNA methylation drives a new path in gastric cancer early detection: current impact and prospects. Genes Dis 2023; 11: 847-60.
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Lofton-Day C, Model F, Devos T, et al. DNA methylation biomarkers for blood-based colorectal cancer screening. Clin Chem 2008; 54: 414-23.
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Chung DC, Gray DM 2nd, Singh H, et al. A cell-free DNA blood-based test for colorectal cancer screening. N Engl J Med 2024; 390: 973-83.
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Zhang Q, Du Z, Wang X, et al. Cell-free nucleic acid as promising diagnostic biomarkers for gastric cancer: a systematic review. J Cancer 2024; 15: 2900-12.
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Tang H, Ma X, Zhou L, et al. Distinct performance of methylated SEPT9 in upper and lower gastrointestinal cancers and combined detection with protein markers. Genet Test Mol Biomarkers 2022; 26: 239-48.
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Nie Y, Gao X, Cai X, et al. Combining methylated SEPTIN9 and RNF180 plasma markers for diagnosis and early detection of gastric cancer. Cancer Commun (Lond) 2023; 43: 1275-9.
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Cao CQ, Chang L, Wu Q. Circulating methylated Septin 9 and ring finger protein 180 for noninvasive diagnosis of early gastric cancer. Transl Cancer Res 2020; 9: 7012-21.
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Xu J, Song J, Wang T, et al. A combination of methylation and protein markers is capable of detecting gastric cancer detection by combined markers. Epigenomics 2021; 13: 1557-70.
| eISSN: | 1896-9151 |
| ISSN: | 1734-1922 |
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